Why the study?
Does intravenous streptokinase reduce infarct size and improve left ventricular function in patients with acute myocardial infarction within 3 hours of symptom onset?
Population
64 patients with acute myocardial infarction within 3 hours after the onset of symptoms
Comparison
Streptokinase 1,500,000 IU via 1-hour… vs Conventional therapy
Design
RCT, randomly assigned
Follow-up
5 weeks
Authors
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Supports early IV streptokinase in AMI within 3 h; extends RCT evidence for thrombolysis on myocardial salvage.
Does intravenous streptokinase reduce infarct size and improve left ventricular function in patients with acute myocardial infarction within 3 hours of symptom onset?
Early intravenous streptokinase infusion in acute myocardial infarction reduces infarct size and improves left ventricular function, with benefits closely correlated to vessel patency.
Durand et al. (1987) studied this question.
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