Early mortality in prophylactic implantable cardioverter-defibrillator recipients: development and validation of a clinical risk score
Why the study?
Can a clinical risk score predict early mortality (<1 year) in prophylactic ICD recipients?
Population
1,567 prophylactic ICD recipients with ischaemic cardiomyopathy or dilated cardiomyopathy across a…
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
May aid stratification of early mortality risk in prophylactic ICD recipients; hypothesis-generating pending prospective validation.
Structured PICO
Can a clinical risk score predict early mortality (<1 year) in prophylactic ICD recipients?
P
Population
1,567 prophylactic ICD recipients with ischaemic cardiomyopathy or dilated cardiomyopathy (LVEF ≤35%) across a prediction cohort (n=861) and validation cohort (n=706).
I
Intervention
Clinical risk score based on age ≥75 years, LVEF ≤ 20%, history of atrial fibrillation, and eGFR ≤30 mL/min/1.73 m(2)
O
Outcome
All-cause mortality at 1 yearhard clinical
A simple 4-factor clinical risk score can effectively identify prophylactic ICD candidates at high risk for early mortality, aiding in patient selection and avoiding non-beneficial device therapy.
Cite This Study
Kraaier et al. (2013) studied this question.