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July 4, 2021BMC Cardiovascular DisordersOpen Access

Identification of candidate biomarkers and therapeutic agents for heart failure by bioinformatics analysis

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Why the study?

Heart failure affects millions of people globally, creating a need to screen and verify hub genes involved in developmental heart failure and explore active drug molecules.

Population

366 samples, including 200 heart failure samples and 166 non heart failure samples

Comparison

Heart failure samples vs non heart failure samples

Design

Bioinformatics analysis of high throughput sequencing dataset GSE141910

Authors

VKVijayakrishna KolurVivus Heart HospitalBVBasavaraj VastradAl-Ameen College of PharmacyCVChanabasayya VastradSri Dharmasthala Manjunatheshwara College of Dental Sciences & Hospital

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Implication

Hypothesis-generating for HF hub genes and candidate drugs; requires experimental and clinical validation before any practice implications.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Kolur et al. (2021) studied this question.

synapsesocial.com/papers/6a1bc52bc97d63156a5ee801https://doi.org/10.1186/s12872-021-02146-8

Topics

Heart failureHFrEF treatment
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