The study describes the phonocardiographic and apex cardiogram features of patients with systolic click-late systolic murmur syndrome, distinguishing between isolated cases and those with rheumatic mitral valve disease.
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Isolated click-murmur may differ from rheumatic mitral disease; case series leaves open broader diagnostic validation.
A series of 46 patients with a systolic click and mid-late systolic murmur has been described. All had detailed phonocardiographic and external pulse wave studies. Nine patients also had cardiac catheter studies, of whom 8 had left ventricular cineangiography. They were divided into two groups. In group i there were 38 patients where the systolic click and murmur were an isolated finding, and in group 2 there were 8 patients where there was associated chronic rheumatic mitral valve disease.
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Epstein et al. (1973) studied this question.
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