What question did this study set out to answer?

To determine whether patients with mitral leaflet prolapse also exhibit prolapse of the tricuspid valve leaflets.

December 14, 1972New England Journal of Medicine

Prolapse of Both Mitral and Tricuspid Leaflets in Systolic Murmur-Click Syndrome

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Why the study?

Does right ventriculography reveal tricuspid valve prolapse in patients with mitral valve prolapse compared to controls?

Population

25 patients (13 with proved prolapsed mitral leaflets and 12 controls without prolapse)

Comparison

Right ventriculography vs Patients without mitral valve prolapse

Design

Case-control

Authors

AGAlden S. GoochDeborah Heart and Lung Center VMVladir MaranhãoDeborah Heart and Lung Center GSGregory Scampardonis401 General Military Hospital of Athens

Discussion

Member takes

Implication

Tricuspid prolapse may accompany mitral valve prolapse; leaves open whether this extends to routine evaluation or management.

Key Points

To determine whether patients with mitral leaflet prolapse also exhibit prolapse of the tricuspid valve leaflets.
Conducted right ventriculography to examine tricuspid valves in 13 patients with confirmed mitral leaflet prolapse.
Evaluated 12 control individuals without prolapse for comparison.
Late systolic prolapse of the tricuspid leaflets occurred in 6 of the 13 patients with mitral valve prolapse, predominantly affecting the inferior leaflet.
One patient exhibited a mid-late systolic murmur at the lower left sternal border during inspiration, serving as a clinical indicator of tricuspid involvement.

Structured PICO

Does right ventriculography reveal tricuspid valve prolapse in patients with mitral valve prolapse compared to controls?

Population

25 patients (13 with proved prolapsed mitral leaflets and 12 controls without prolapse)

Intervention

Right ventriculography

Comparator

Patients without mitral valve prolapse

Outcome

Presence of tricuspid leaflet prolapsesurrogate

The syndrome of prolapsed leaflets can involve both atrioventricular valves, with tricuspid prolapse frequently co-occurring with mitral valve prolapse.

Cite This Study

Gooch et al. (1972) studied this question.

synapsesocial.com/papers/6a72cf475db6ec1d621ae339 https://doi.org/10.1056/nejm197212142872403

Topics

Valvular heart disease

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Prolapse of Both Mitral and Tricuspid Leaflets in Systolic Murmur-Click Syndrome

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Prolapse of Both Mitral and Tricuspid Leaflets in Systolic Murmur-Click Syndrome

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider