What does this research mean for the field?

Right atrial maximal volume can be accurately estimated using biplane cineangiocardiography, establishing normative values based on body surface area and demonstrating significant volume increases in patients with right heart conditions such as atrial septal defect. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.ESTABLISHES_NEW_DIRECTION.

What question did this study set out to answer?

The aim is to develop a reliable methodology for measuring right atrial volumes using biplane cineangiocardiography.

April 1, 1974CirculationOpen Access

Right Atrial Volume Measurements from Biplane Cineangiocardiography

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Why the study?

Can right atrial maximal volume be accurately estimated from biplane cineangiograms to evaluate alterations in right heart structure and function?

Population

57 patients undergoing diagnostic cardiac catheterization, plus 14 human right atria casts for methodology…

Comparison

Right atrial volume measurement using biplane… vs Known volume from right atrial casts…

Design

Cross-sectional

Authors

TGT.P. GrahamUC San Diego Health System GAGerald F. AtwoodDuke University SFScott FaulknerSaint Thomas West Hospital

Discussion

Member takes

Implication

Validates biplane cineangiographic RA volume estimation; leaves open its clinical utility pending prospective validation.

Key Points

The aim is to develop a reliable methodology for measuring right atrial volumes using biplane cineangiocardiography.
Calculated right atrial volumes in 29 patients during diagnostic cardiac catheterization.
Validated methodology against right atrial casts of 14 human right atria.
Evaluated the correlation of RA Max with body surface area using exponential equations.
Achieved correlation for known and calculated RA volume with Simpson's method (r = 0.999) and area-length method (r = 0.998).
RA Max normalized for body size was significantly less in infants under one year compared to older patients.
Observed an increase in RA Max averaging 198% of normal in patients with atrial septal defect or anomalous pulmonary venous return.

Structured PICO

Can right atrial maximal volume be accurately estimated from biplane cineangiograms to evaluate alterations in right heart structure and function?

Population

57 patients undergoing diagnostic cardiac catheterization (29 with normal right hearts, 14 with atrial septal defect or anomalous pulmonary venous return, and 14 with moderate to severe pulmonary stenosis), plus 14 human right atria casts for methodology validation.

Intervention

Right atrial volume measurement using biplane cineangiocardiography (calculated via Simpson's rule or area-length method).

Comparator

Known volume from right atrial casts (for validation); comparisons also made between normal right hearts and those with right heart pathology.

Outcome

Correlation of calculated right atrial volume with known volume, and relationship between right atrial maximal volume (RA Max) and body surface area (BSA).surrogate

Biplane cineangiocardiography provides highly accurate estimates of right atrial volume, which correlates strongly with body surface area and increases significantly in conditions with right heart volume or pressure overload.

Cite This Study

Graham et al. (1974) studied this question.

synapsesocial.com/papers/6a1bc63f5b8f4ede65a9008b https://doi.org/10.1161/01.cir.49.4.709

Topics

Congenital heart disease adults

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Right Atrial Volume Measurements from Biplane Cineangiocardiography

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Right Atrial Volume Measurements from Biplane Cineangiocardiography

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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