What does this research mean for the field?

Apoptosis characterizes the onset of pathology in dystrophin-deficient muscle and precedes any detectable necrotic changes, indicating that cell death begins as an apoptotic rather than purely necrotic process. Novelty: ClaimNovelty.CONTRADICTORY. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

June 1, 1995Journal of Cell Science

Apoptosis precedes necrosis of dystrophin-deficient muscle

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Authors

JTJames G. Tidball DADouglas E. Albrecht BLBeth E. Lokensgard

Discussion

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Overview

Apoptosis may contribute to dystrophin-deficient fiber death; challenges necrosis consensus in mdx models but leaves open human DMD relevance.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Tidball et al. (1995) studied this question.

synapsesocial.com/papers/6a1bc64fd54006be995ef1ff https://doi.org/10.1242/jcs.108.6.2197

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June 1, 1995Journal of Cell Science

Apoptosis precedes necrosis of dystrophin-deficient muscle

View Full Paper

Ask AI

Bookmark

Authors

JTJames G. Tidball DADouglas E. Albrecht BLBeth E. Lokensgard

Discussion

Member takes

Overview

Apoptosis may contribute to dystrophin-deficient fiber death; challenges necrosis consensus in mdx models but leaves open human DMD relevance.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Tidball et al. (1995) studied this question.

synapsesocial.com/papers/6a1bc64fd54006be995ef1ff https://doi.org/10.1242/jcs.108.6.2197

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