Why the study?
Does blood pressure lowering therapy reduce the risk of stroke and coronary heart disease in patients with NIDDM and mild hypertension?
Population
Patients with non-insulin-dependent diabetes mellitus (NIDDM) and mild hypertension
Comparison
Blood pressure lowering therapy vs No treatment or different blood pressure…
Design
Review
Authors
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May support larger absolute benefits in diabetics with mild hypertension; hypothesis-generating extrapolation leaves practice unchanged pending direct trials.
Does blood pressure lowering therapy reduce the risk of stroke and coronary heart disease in patients with NIDDM and mild hypertension?
While treating mild hypertension in diabetic patients may offer greater absolute cardiovascular benefits than in nondiabetics, the number needed to treat remains high and must be weighed against potential adverse effects on quality of life.
John Yudkin (1991) studied this question.
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