Discusses the analytical characteristics of high-sensitivity cardiac troponin assays for the detection of myocardial injury and diagnosis of myocardial infarction.
Supports precise hs-cTn use for MI diagnosis; extends analytical validation from RCT data.
Background: Cardiac troponins I (cTnI) and T (cTnT) have received international endorsement as the standard biomarkers for detection of myocardial injury, for risk stratification in patients suspected of acute coronary syndrome, and for the diagnosis of myocardial infarction. An evidence-based clini...
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Apple et al. (2014) studied this question.
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