What does this research mean for the field?

In patients with idiopathic prolapsed mitral leaflet syndrome, the severity of mitral regurgitation, clinical presentation, and electrocardiographic abnormalities correlate with the specific extent of leaflet prolapse and ventricular asynergy. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To explore the angiographic-clinical correlations in patients with prolapsed mitral leaflet syndrome and its associated outcomes.

November 1, 1976CirculationOpen Access

Idiopathic prolapsed mitral leaflet syndrome. Angiographic-clinical correlations.

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Why the study?

What are the angiographic correlates of different clinical auscultatory presentations in patients with idiopathic prolapsed mitral leaflet syndrome?

Key Points

To explore the angiographic-clinical correlations in patients with prolapsed mitral leaflet syndrome and its associated outcomes.
Analyzed 59 patients with prolapsed mitral leaflet syndrome classified into three groups based on clinical findings.
Evaluated presence of murmurs and systolic clicks, as well as angiographic findings like leaflet prolapse type.
Correlated clinical findings with mitral regurgitation severity and cardiac function.
Patients with triple scallop prolapse and combined leaflet prolapse showed severe mitral regurgitation and atrial fibrillation.
Isolated posterior leaflet prolapse was most common in group II, while group III had higher incidences of combined prolapse.
Segmental anterior dysfunction with preserved ejection fraction was common, especially among patients with asynergy.

Structured PICO

What are the angiographic correlates of different clinical auscultatory presentations in patients with idiopathic prolapsed mitral leaflet syndrome?

Population

59 patients with prolapsed mitral leaflet syndrome (8 with nonejection systolic clicks, 20 with early, mid or late systolic murmurs with or without a systolic click, and 31 with pansystolic murmurs).

Outcome

Angiographic-clinical correlations (leaflet prolapse patterns, mitral regurgitation severity, and ventricular asynergy)surrogate

Clinical auscultatory findings in mitral valve prolapse correlate strongly with specific angiographic anatomic patterns of leaflet involvement, regurgitation severity, and ventricular asynergy.

Discussion

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Implication

Murmur timing may noninvasively suggest prolapse complexity and regurgitation severity; leaves open whether this informs referral or management decisions.

Cite This Study

Ranganathan et al. (1976) studied this question.

synapsesocial.com/papers/6a1bcc3d9dc17f23939cc359 https://doi.org/10.1161/01.cir.54.5.707

Topics

Mitral valve intervention

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Implication

Murmur timing may noninvasively suggest prolapse complexity and regurgitation severity; leaves open whether this informs referral or management decisions.

Idiopathic prolapsed mitral leaflet syndrome. Angiographic-clinical correlations.

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Idiopathic prolapsed mitral leaflet syndrome. Angiographic-clinical correlations.

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider