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The study aims to evaluate the safety of celecoxib in postoperative orthopaedic patients with documented sulfonamide allergies.

Safety of Celecoxib in Postoperative Patients With Documented Sulfonamide Allergies

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The study aims to evaluate the safety of celecoxib in postoperative orthopaedic patients with documented sulfonamide allergies.
Retrospective cohort study conducted at a single tertiary center.
Inclusion of orthopaedic surgery patients with sulfonamide allergies who received celecoxib postoperatively, from January 2020 to December 2022.
Review of postoperative notes, telephone encounters, and emergency department records for allergic reactions.
Sixty-one patients met inclusion criteria with 21.3% presenting for various issues post-surgery.
Two patients reported allergic reactions linked to other medications, not celecoxib.
One gastrointestinal bleed occurred in a patient also taking aspirin, but no reactions were attributed to celecoxib.

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Retrospective cohort study evaluates celecoxib safety in postoperative patients with sulfonamide allergies, suggesting safe use for pain management.

Snowden et al. (2026) studied this question.

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Retrospective cohort study evaluates celecoxib safety in postoperative patients with sulfonamide allergies, suggesting safe use for pain management.