Why the study?
Does PVC treatment reduce ventricular arrhythmic burden and prevent left atrial dilation and LVEF decline in patients with PVC burden > 5000 beats/day?
Population
286 patients with premature ventricular complex (PVC) burden > 5000 beats/day on Holter monitoring
Comparison
PVC treatment vs Observation (no PVC treatment)
Design
Cohort
Follow-up
mean 9.40 ± 6.70 months and 9.40 ± 5.52 months
Authors
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May support PVC treatment in high-burden patients; leaves open need for RCTs to confirm effects on LA size and LVEF.
Does PVC treatment reduce ventricular arrhythmic burden and prevent left atrial dilation and LVEF decline in patients with PVC burden > 5000 beats/day?
Treatment of premature ventricular complexes in patients with a high burden (>5000 beats/day) reduces ventricular arrhythmic burden and may prevent left atrial dilation and LVEF decline.
Chen et al. (2020) studied this question.