October 1, 2002Hypertension
Impaired Fasting Glucose, Blood Pressure and Cardiovascular Disease Mortality
Why the study?
Does impaired fasting glucose combined with moderate systolic hypertension increase cardiovascular mortality in men without known ischemic cardiac disease?
Population
63,443 consecutive men undergoing a routine health examination. Excluded: known ischemic cardiac disease and…
Comparison
Impaired fasting glucose with or without… vs Normal fasting glucose with normal systolic…
Design
Cohort
Follow-up
8 years
Authors
Discussion
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Member takes
Implication
May warrant closer monitoring in men with impaired fasting glucose and moderate systolic hypertension; leaves open whether targeted interventions improve outcomes.
Structured PICO
Does impaired fasting glucose combined with moderate systolic hypertension increase cardiovascular mortality in men without known ischemic cardiac disease?
P
Population
63,443 consecutive men (ages 21 to 60 years) undergoing a routine health examination. Excluded: known ischemic cardiac disease and treatment for diabetes or hypertension.
I
Intervention
Impaired fasting glucose (fasting plasma glucose 6.1 to 6.9 mmol/L [110 to 125 mg/dL]) with or without moderate systolic hypertension (140 to 159 mm Hg)
C
Comparator
Normal fasting glucose (fasting plasma glucose 3.9 to 6.0 mmol/L) with normal systolic blood pressure (<140 mm Hg)
O
Outcome
8-year cardiovascular mortalityhard clinical
The presence of moderate systolic hypertension identifies subjects with impaired fasting glucose who are at significantly increased risk of cardiovascular and overall mortality.
Cite This Study
Henry et al. (2002) studied this question.