Why the study?
How do left ventricular diastolic flow dynamics change in healthy newborns during the neonatal transition period?
How do left ventricular diastolic flow dynamics change in healthy newborns during the neonatal transition period?
Intraventricular flow dynamics assessed by blood speckle tracking can describe changes in cardiac physiology during normal postnatal cardiovascular adaptation.
Provides normative neonatal LV flow data; extends postnatal adaptation knowledge but leaves open utility in congenital disease.
Assessment of left ventricular flow dynamics is highly feasible using high-frame rate echocardiography-based blood speckle tracking. In healthy newborns, left ventricular diastolic kinetic energy, energy loss, and vorticity significantly change during the first weeks, stabilizing after 6-8 wk, whereas intraventricular pressure difference continues to increase until 6 mo of age. These findings indicate that intraventricular flow dynamics can describe changes in cardiac physiology contributing to normal postnatal cardiovascular adaptation, maturation, and function.
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Sørensen et al. (2025) studied this question.
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