Left ventricular hypertrophy without coronary artery disease can cause variable ST-T abnormalities, including non-specific changes that cannot be distinguished from coronary artery disease, potentially affecting the accuracy of ECG criteria for LVH.
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Non-specific ST-T changes occur in 37% of LVH without CAD and may confound ischemia detection; challenges classic strain pattern and leaves ECG criteria open.
Huwez et al. (1992) studied this question.
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