Why the study?
Can bipolar and unipolar intramural potentials accurately classify normal versus infarcted myocardium in a canine model?
Can bipolar and unipolar intramural potentials accurately classify normal versus infarcted myocardium in a canine model?
This preclinical study established a database to evaluate the ability of intramural potentials to classify normal versus infarcted myocardium in dogs.
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Supports further investigation of intramural potentials for tissue characterization; leaves open translation from canine models to clinical use.
The purpose of this study is to evaluate how well bipolar and intramural potentials are able to classify the state of the myocardium (normal or infarcted) proximal to the electrode recording sites. Nine mongrel dogs with anterior myocardial infarcts were used to generate a database for the study. Classification of the myocardium as normal or infarcted was attempted from potentials recorded in and around the infarcted region using electrodes within plunge needles. In addition to the potentials, the database contains the locations of the plunge needles, the grossly visible borders of the infarcts, and the epicardium and endocardium of both ventricles.
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Claydon et al. (1985) studied this question.
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