Why the study?
Does diabetes worsen early and late outcomes in patients undergoing coronary artery bypass surgery?
Does diabetes worsen early and late outcomes in patients undergoing coronary artery bypass surgery?
While early mortality after CABG is similar between diabetic and non-diabetic patients, diabetes is associated with significantly worse long-term survival.
OBJECTIVE: To determine the impact of diabetes on outcome after coronary artery bypass surgery. DESIGN: We matched 866 diabetic patients with non-diabetic controls in regards to gender, age, left ventricular ejection fraction, body mass index, presence of unstable angina and history of myocardial infarction, and day of surgery. The 30-d mortality and morbidity were evaluated with univariate analysis and survival and freedom from cardiac death were assessed with the Kaplan-Meier method. RESULTS: Follow-up time was 69+/-37 months. The 30-d mortality was 2.0% in the diabetic group and 1.0% in the non-diabetic group (p=0.15). Postoperative morbidity did not differ between groups. Cumulative 5- and 10-year survival rates were 89 and 71% in diabetics and 94 and 84% in non-diabetics (p=0.001). During follow-up, there was no difference between groups in regards to repeat revascularization. CONCLUSIONS: The 30-d mortality was equally low in diabetic and non-diabetic patients with severe coronary artery disease. However, long-term survival was significantly lower in the diabetic group than in the non-diabetic group.
No takes yet. Share an insight, caveat, or question.
Hakala et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: