Why the study?
Does diabetes mellitus increase mortality and major cardiovascular events in patients undergoing coronary artery bypass graft surgery?
Does diabetes mellitus increase mortality and major cardiovascular events in patients undergoing coronary artery bypass graft surgery?
Diabetic patients undergoing CABG have acceptable short-term operative mortality and major cardiovascular event rates that are not statistically significantly different from non-diabetic patients.
DM may elevate short-term morbidity post-CABG; leaves open whether targeted perioperative strategies improve outcomes in diabetics.
Background Diabetes mellitus (DM) is considered as mortality and morbidity risk factor for coronary artery bypass graft surgery (CABG). Studies revealed that there are controversies concerning the results of a post coronary surgery diabetic patients. The aim of our study was the evaluation of the short-term outcomes in this group of patients. Methods This was a single-center retrospective study of 180 patients that were subjected to CABG between January 2014 and January 2016 in Zagazig University Hospital, Zagazig, Egypt. Sixty-one patients (34%) were diabetic (group I) and 119 patients (66%) were non-diabetic (group II). During follow-up period the hospital mortality, complications and major cardiovascular events were analyzed. All patients admitted with a diagnosis of diabetes had an HbA1c ≥ 6.5% or fasting blood glucose (FBG) ≥ 126 mg/dL (7.0 mmol/L). Results Operative mortality was 3% (n = 2) in the diabetic group and 1% (n = 1) in non-diabetic patients (p = 0.3). Euro score was predictably higher in diabetic patients (1.2 vs 0.84, p = 0.001). The study of the risk factors associated with hospital complications revealed that the absence of diabetes was a protective factor for hospital complications but statistically insignificant. The rate of major cardiovascular events at 2 years period of follow-up in diabetic and non-diabetic groups was (12/50) 24% and (16/93)17%, respectively (p = 0.43). Conclusions The improvement in management of DM patients leads to acceptable operative mortality post-CABG and decrease the incidence of complications and events in the short-term follow-up period.
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Moursi et al. (2017) studied this question.
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