Why the study?
Intravenous broad-spectrum antibiotics for non-operative management of uncomplicated acute appendicitis are usually given in hospital, and only one study has described outpatient management.
Does outpatient non-operative management prevent 30-day appendectomy as effectively as inpatient non-operative management in patients with uncomplicated acute appendicitis?
Population
668 consecutive patients with uncomplicated acute appendicitis
Comparison
Outpatient non-operative management vs inpatient non-operative management
Design
Multicentre retrospective non-inferiority study
Follow-up
30 days
Authors
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May support outpatient non-operative management; leaves open confirmation by randomized trials before practice change.
Does outpatient non-operative management prevent 30-day appendectomy as effectively as inpatient non-operative management in patients with uncomplicated acute appendicitis?
Outpatient non-operative management of uncomplicated acute appendicitis is non-inferior to inpatient management regarding 30-day appendectomy rates and significantly reduces hospital length of stay.
Ceresoli et al. (2023) studied this question.
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