Early cardiovascular evaluation is necessary for children with suspected Marfan's syndrome due to the high frequency of mitral valve involvement.
May support mitral-focused evaluation in children with Marfan syndrome; extends adult aortic paradigm but leaves open prospective validation.
Cardiovascular disease in Marfan's syndrome presenting in childhood affects the mitral valve more often than the aortic valve or the aorta, as in adults. Early evaluation of the cardiovascular system is necessary for any child in whom Marfan's syndrome is suspected.
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Marlow et al. (1987) studied this question.
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