Why the study?
What are the mechanisms and consequences of left atrial mechanical dysfunction following pulmonary vein antrum isolation for atrial fibrillation?
What are the mechanisms and consequences of left atrial mechanical dysfunction following pulmonary vein antrum isolation for atrial fibrillation?
This review highlights the clinical impact of left atrial mechanical dysfunction after atrial fibrillation ablation, emphasizing its role in worsening hemodynamics and increasing thromboembolic risk.
Suggests post-ablation LA function monitoring; leaves open prospective validation of risk-reduction strategies.
The article presents new insights into the left atrial mechanical function, its main components and remodeling mechanisms after pulmonary vein antrum isolation. Left atrium is a cardiac chamber that transports blood. Being a complex «organ» both in anatomical and functional terms, it responds to hemodynamic derangements, the impact of humoral and vegetative factors. Structural, mechanical and electrical remodeling of the left atrium play a key role in the arrhythmogenesis of atrial fibrillation, as well as in the mechanism of arrhythmia maintenance. Left atrial mechanical dysfunction following catheter ablation of atrial fibrillation significantly affects intracardiac hemodynamics, worsens patients' well-being, and increases the risk of thromboembolic complications both in the immediate and long-term postoperative period.
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Мамчур et al. (2018) studied this question.
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