Why the study?
Does switching to low dose oral contraceptives reduce blood pressure in women with hypertension induced by high dose oral contraceptives?
Does switching to low dose oral contraceptives reduce blood pressure in women with hypertension induced by high dose oral contraceptives?
Switching from high to low dose oral contraceptives significantly lowers blood pressure in women with oral contraceptive-induced hypertension, though it may not fully normalize after one year.
Supports cautious switch to low-dose OCs in OC-induced hypertension; hypothesis-generating and should not yet change practice.
Thirty women with hypertension induced by oral contraceptives containing 50 μg oestrogen and 1 to 4 mg. progestagen showed a marked significant fall in blood pressure when given either (a) a combination of 30 μg ethinyloestradiol with 150 to 250 μg levonorgestrel or (b) 350 μg norethisterone alone. One year after changing to either of these low dose preparations blood pressure had not fully returned to pre-oral contraceptive levels.
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R. J. Weir (1982) studied this question.
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