Why the study?
Early hours of myocardial infarction carry substantial mortality, prompting this study to measure and compare levels of cardiac and inflammatory markers between STEMI and NSTEMI.
Are there differences in inflammatory markers (C-reactive protein, D-dimer) between STEMI and NSTEMI patients?
Are there differences in inflammatory markers (C-reactive protein, D-dimer) between STEMI and NSTEMI patients?
Inflammatory markers such as C-reactive protein and D-dimer differ significantly between STEMI and NSTEMI patients.
Differences in CRP and D-dimer between STEMI and NSTEMI are hypothesis-generating; should not yet change practice.
Background The first few hours before going to the hospital are the most dangerous for a person having a heart attack. Death can occur during this period in 20–30% of people who have a heart attack, so it is necessary to seek immediate medical care when people suspect that they are having a heart attack. This research aims to study and measure the levels of certain substances (called markers). cardiac markers and inflammatory markers, and a comparison of their mean between the two types of infarction. Methods and materials: This study was conducted on 100 male and female patients from Damascus Hospital, where all patients with myocardial infarction (STEMI-NSTEMI) who met inclusion and exclusion criteria were admitted and our study relied on the retrospective and cross sectional study method. Results The sample included 100 male and female patients, all of whom had myocardial infarction (STEMI-NSTEMI), where the percentage of males in the study was 78% and the percentage of females was 22%. The mean of age of the patients was 55.47 years with a standard deviation of 10.318 years. The percentage of smokers was 63%. as for the type of infarction, the majority were Patients have STEMI type, and by studying the relationships, it was found that there was no statistically significant relationship between the type of infarction and the medical history, and between the type of infarction and complications, where p.value > 0.05. Conclusion There are statistically significant differences when comparing the mean values of C-reactive protein (CRB) in the two types of infarction (STEMI-NSTEMI). The product of fibrin degradation (D. dimer) in the two types of infarction (STEMI-NSTEMI) where p.value < 0.05.
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Marwan et al. (2023) studied this question.
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