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January 1, 2003Hypertension ResearchOpen Access

Molecular Analysis of the Structure and Function of the Angiotensin II Type 1 Receptor

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Authors

SMShin-ichiro MiuraFukuoka UniversityKSKeijiro SakuKanazawa UniversitySKSadashiva S. KarnikHeart Failure & Transplant

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Implication

Molecular insights into AT1 receptors may enable new strategies; leaves open clinical translation for hypertension.

Key Points

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Cite This Study

Miura et al. (2003) studied this question.

synapsesocial.com/papers/6a1be8fbfc87fd06169cea79https://doi.org/10.1291/hypres.26.937
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cross Talk between Angiotensin II Type 1 and Type 2 Receptors: Cellular Mechanism of Angiotensin Type 2 Receptor-Mediated Cell Growth Inhibition.1999 · 43 citations
  2. 2Local Angiotensin II-Generating System in Vascular Tissues: The Roles of Chymase.2001 · 69 citations
  3. 3Role of Aromaticity of Agonist Switches of Angiotensin II in the Activation of the AT1 Receptor1999 · 101 citations
  4. 4Angiotensin IV Is a Potent Agonist for Constitutive Active Human AT1 Receptors2002 · 82 citations
  5. 5Angiotensin II Type 2 Receptor Gene Transfer Downregulates Angiotensin II Type 1a Receptor in Vascular Smooth Muscle Cells2002 · 66 citations