Population
Human umbilical vein endothelial cells, NIH3T3 cells, and reporter rat fetal lung fibroblasts
Design
Preclinical
Authors
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No immediate clinical impact on vascular disease; leaves open targeted human eNOS research in endothelial biology.
The successful cloning and functional expression of human endothelial nitric oxide synthase provides a critical foundation for studying its role in vascular tone regulation.
Janssens et al. (1992) studied this question.
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