Population
Chicken cardiac muscle (ultrathin frozen sections of fixed tissue)
Design
Preclinical
Authors
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Reinforces vinculin's membrane-proximal anchoring role in avian cardiac intercalated discs; leaves open translation to mammalian or human myocardium.
In chicken cardiac muscle, vinculin is situated closer to the membrane than alpha-actinin at the fascia adherens, suggesting it participates in linking actin-containing microfilament bundles to membranes.
Tokuyasu et al. (1981) studied this question.
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