Why the study?
Do calcium channel blockers improve outcomes in patients who have suffered a myocardial infarction?
Population
Patients who suffered a myocardial infarction
Comparison
Calcium channel blockers (including diltiazem) vs Beta-blockade or standard care
Design
Review
Authors
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Supports caution against routine calcium channel blocker use post-MI; leaves open diltiazem's targeted role in non-Q-wave cases.
Do calcium channel blockers improve outcomes in patients who have suffered a myocardial infarction?
Calcium channel blockers are generally not recommended for routine use post-myocardial infarction, especially in Q-wave MI or with LV dysfunction, though diltiazem may benefit non-Q-wave MI patients.
Alan E. Skolnick (1989) studied this question.
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