Deep gray matters iron deposition is positively associated with white matter hyperintensity in hypertension

Figures

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  FIGURE 1. Upper row: Quantitative susceptibility mapping (QSM) of a 62‐year‐old male. Lower row: Region of, interest (ROI) was delineated on the QSM, including 1 = frontal white matter (FWM), 2 = caudate nucleus, head (CN), 3 = globus pallidus (GP), 4 = putamen (PU), 5 = thalamus (TH), 6 = substantia nigra (SN), 7 = rednucleus (RN), 8 = dentate nucleus (DN).

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  FIGURE 2. Diagram of the RI and RII region. The region inside the red line represents the RI of the right GP and, the purple region represents the distribution of the RII.

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  FIGURE 3. Diagram showing the partial correlation analysis between deep gray matters susceptibilities and WMH, scores. (A) Correlation between RI susceptibilities (right PU) and WMH scores. (B–F) correlation between RII, susceptibilities (bilateral CN, PU, RN, SN, and DN) and WMH scores.

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  FIGURE 4. Diagram showing the partial correlation analysis between deep gray matters susceptibilities and, periventricular or deep WMH scores. (A–F) correlation between susceptibilities (bilateral GP, PU, RN, SN, DN, and left CN) and periventricular WMH scores. (G–H) correlation between susceptibilities (bilateral CN and PU), and deep WMH scores in the RI or RII analysis.

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  FIGURE 5. Diagram showing the partial correlation analysis between deep gray matters susceptibilities and WMH, scores in the older (>61 years old) group. (A–C) Correlation between RI susceptibilities (right PU, left RN, and, bilateral SN) and WMH scores. (D–H) Correlation between RII susceptibilities (bilateral CN, PU, SN, DN, and, left RN) and WMH scores.