What does this research mean for the field?

Salmonid fish fast, slow, and cardiac muscle tropomyosins possess distinct sequence variations—none of which correspond to a β-type tropomyosin—and exhibit differing thermal unfolding profiles and viscosity characteristics. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

December 1, 1996European Journal of BiochemistryOpen Access

Further Characterisation of Fast, Slow and Cardiac Muscle Tropomyosins from Salmonid Fish

View Full Paper

Ask AI

Bookmark

Population

Cardiac muscle and slow myotomal muscle of mature brown trout (Salmo trutta)

Comparison

cDNA library construction, sequencing… vs Atlantic salmon fast myotomal TM, chicken…

Design

Preclinical

Authors

DJDonna M. JackmanMemorial University of Newfoundland DWDeena WaddletonTransCanada (Canada)BYBanfield YounghusbandMemorial University of Newfoundland

Discussion

Member takes

Overview

Trout TM data offer no clinical guidance; leaves open comparative studies on isoform thermal stability in poikilotherms.

Structured PICO

Population

Cardiac muscle and slow myotomal muscle of mature brown trout (Salmo trutta)

Intervention

cDNA library construction, sequencing, calorimetry, cloning, and expression of tropomyosin isoforms

Comparator

Atlantic salmon fast myotomal TM, chicken cardiac TM, and skeletal α-TMs

Outcome

Sequence identity, thermal unfolding profiles, and relative viscosity of tropomyosin isoformssurrogate

The study characterizes the sequence and biophysical properties of fast, slow, and cardiac muscle tropomyosins from salmonid fish, revealing distinct structural and thermal unfolding profiles.

Cite This Study

Jackman et al. (1996) studied this question.

synapsesocial.com/papers/6a1bf2fc27b545b111a93ee9 https://doi.org/10.1111/j.1432-1033.1996.0363r.x

View Full Paper

Ask AI

Bookmark

December 1, 1996European Journal of BiochemistryOpen Access

Further Characterisation of Fast, Slow and Cardiac Muscle Tropomyosins from Salmonid Fish

View Full Paper

Ask AI

Bookmark

Population

Cardiac muscle and slow myotomal muscle of mature brown trout (Salmo trutta)

Comparison

cDNA library construction, sequencing… vs Atlantic salmon fast myotomal TM, chicken…

Design

Preclinical

Authors

DJDonna M. JackmanMemorial University of Newfoundland DWDeena WaddletonTransCanada (Canada)BYBanfield YounghusbandMemorial University of Newfoundland

Discussion

Member takes

Overview

Trout TM data offer no clinical guidance; leaves open comparative studies on isoform thermal stability in poikilotherms.

Structured PICO

Population

Cardiac muscle and slow myotomal muscle of mature brown trout (Salmo trutta)

Intervention

cDNA library construction, sequencing, calorimetry, cloning, and expression of tropomyosin isoforms

Comparator

Atlantic salmon fast myotomal TM, chicken cardiac TM, and skeletal α-TMs

Outcome

Sequence identity, thermal unfolding profiles, and relative viscosity of tropomyosin isoformssurrogate

The study characterizes the sequence and biophysical properties of fast, slow, and cardiac muscle tropomyosins from salmonid fish, revealing distinct structural and thermal unfolding profiles.

Cite This Study

Jackman et al. (1996) studied this question.

synapsesocial.com/papers/6a1bf2fc27b545b111a93ee9 https://doi.org/10.1111/j.1432-1033.1996.0363r.x

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark