What does this research mean for the field?

Salmonid fish express distinct fast, slow, and cardiac muscle tropomyosin isoforms that differ in their amino acid sequences and thermal unfolding profiles, none of which correspond to beta-type tropomyosins. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

August 1, 1995European Journal of BiochemistryOpen Access

Characterisation of Fast, Slow and Cardiac Muscle Tropomyosins from Salmonid Fish

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Population

Cardiac muscle and slow myotomal muscle of mature brown trout (Salmo trutta)

Comparison

Sequence determination, calorimetry, and… vs Atlantic salmon fast myotomal TM, chicken…

Design

Preclinical

Authors

DHDavid H. HeeleyMemorial University of Newfoundland TBThorben BiegerMemorial University of Newfoundland DWDeena WaddletonTransCanada (Canada)

Discussion

Member takes

Overview

Trout cardiac TM data offer no clinical guidance; extends comparative tropomyosin characterization in fish.

Structured PICO

Population

Cardiac muscle and slow myotomal muscle of mature brown trout (Salmo trutta)

Intervention

Sequence determination, calorimetry, and recombinant expression of tropomyosin (TM) isoforms

Comparator

Atlantic salmon fast myotomal TM, chicken cardiac TM, and skeletal alpha-TMs

Outcome

Tropomyosin sequence identity and thermal unfolding profilessurrogate

This basic science study characterizes the sequence and thermal unfolding properties of fast, slow, and cardiac muscle tropomyosins from salmonid fish, showing cardiac TM is most similar to chicken cardiac TM.

Cite This Study

Heeley et al. (1995) studied this question.

synapsesocial.com/papers/6a1bf2fc27b545b111a93eeb https://doi.org/10.1111/j.1432-1033.1995.tb20803.x

View Full Paper

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August 1, 1995European Journal of BiochemistryOpen Access

Characterisation of Fast, Slow and Cardiac Muscle Tropomyosins from Salmonid Fish

View Full Paper

Ask AI

Bookmark

Population

Cardiac muscle and slow myotomal muscle of mature brown trout (Salmo trutta)

Comparison

Sequence determination, calorimetry, and… vs Atlantic salmon fast myotomal TM, chicken…

Design

Preclinical

Authors

DHDavid H. HeeleyMemorial University of Newfoundland TBThorben BiegerMemorial University of Newfoundland DWDeena WaddletonTransCanada (Canada)

Discussion

Member takes

Overview

Trout cardiac TM data offer no clinical guidance; extends comparative tropomyosin characterization in fish.

Structured PICO

Population

Cardiac muscle and slow myotomal muscle of mature brown trout (Salmo trutta)

Intervention

Sequence determination, calorimetry, and recombinant expression of tropomyosin (TM) isoforms

Comparator

Atlantic salmon fast myotomal TM, chicken cardiac TM, and skeletal alpha-TMs

Outcome

Tropomyosin sequence identity and thermal unfolding profilessurrogate

Cite This Study

Heeley et al. (1995) studied this question.

synapsesocial.com/papers/6a1bf2fc27b545b111a93eeb https://doi.org/10.1111/j.1432-1033.1995.tb20803.x

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

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