Population
Reconstituted skeletal muscle thin filament
Comparison
Fluorescence resonance energy transfer using… vs Presence versus absence of troponin and/or Ca2+
Design
Preclinical
Authors
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Supports Ca2+-dependent thin filament dynamics in vitro; extends prior FRET mapping but leaves open in vivo cardiac relevance.
FRET analysis suggests that a relative movement of the two domains of the actin monomer in a reconstituted thin filament occurs in response to changes in calcium concentration.
Masao Miki (1990) studied this question.
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