What does this research mean for the field?

Both smooth and skeletal beta-tropomyosin mRNAs in chickens are derived from transcripts of a single gene with a unique promoter via a differential splicing mechanism. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

February 1, 1989Journal of Biological ChemistryOpen Access

A single gene codes for the β subunits of smooth and skeletal muscle tropomyosin in the chicken

View Full Paper

Ask AI

Bookmark

Structured PICO

Population

Chicken genomic DNA library and RNAs isolated from various tissues

Intervention

Screening with a full length cDNA corresponding to the beta subunit of smooth muscle tropomyosin

Outcome

Characterization of the locus containing the gene for beta-tropomyosin

Demonstrates that smooth and skeletal beta-tropomyosin mRNAs in chickens are generated from a single gene via differential splicing.

Authors

DLDomenico LibriCentre National de la Recherche Scientifique MLMarc LemonnierAssistance Publique Hôpitaux de Marseille TMThierry MeinnelCentre National de la Recherche Scientifique

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

No direct clinical implications; leaves open whether this single-gene mechanism extends to mammalian tropomyosin isoforms.

Cite This Study

Libri et al. (1989) studied this question.

synapsesocial.com/papers/6a1bf2fc27b545b111a93ef2 https://doi.org/10.1016/s0021-9258(19)81702-7

View Full Paper

Ask AI

Bookmark