What does this research mean for the field?

Rat embryonic fibroblast tropomyosin 1 (TM-1) is a 284-amino acid protein that shares the highest sequence homology with smooth muscle alpha-tropomyosin, with significant sequence divergence from other tropomyosins occurring at amino acids 185-216 and 258-284. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

November 1, 1985Journal of Biological ChemistryOpen Access

Rat embryonic fibroblast tropomyosin 1. cDNA and complete primary amino acid sequence.

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Population

Rat embryonic fibroblast mRNA (cDNA expression library of approximately 80,000 members)

Design

Preclinical

Authors

YYY Yamawaki-KataokaCold Spring Harbor Laboratory DHDavid M. HelfmanKorea Advanced Institute of Science and Technology

Discussion

Member takes

Implication

Adds fibroblast tropomyosin sequence data; leaves open functional or cardiovascular roles pending further study.

Structured PICO

Population

Rat embryonic fibroblast mRNA (cDNA expression library of approximately 80,000 members)

Intervention

Cloning and DNA sequence analysis

Outcome

Amino acid sequence of rat embryonic fibroblast tropomyosin 1 (TM-1)

The study determined the complete primary amino acid sequence of rat embryonic fibroblast tropomyosin 1, revealing its structural homology to smooth muscle alpha-tropomyosin.

Cite This Study

Yamawaki-Kataoka et al. (1985) studied this question.

synapsesocial.com/papers/6a1bf2fc27b545b111a93efa https://doi.org/10.1016/s0021-9258(17)38588-5

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Rat embryonic fibroblast tropomyosin 1. cDNA and complete primary amino acid sequence.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Rat embryonic fibroblast tropomyosin 1. cDNA and complete primary amino acid sequence.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider