Adipose Tissue α-Linolenic Acid and Nonfatal Acute Myocardial Infarction in Costa Rica
Why the study?
Do higher levels of adipose tissue alpha-linolenic acid reduce the risk of nonfatal acute myocardial infarction?
Population
964 subjects in Costa Rica, comprising 482 case patients with a first nonfatal acute MI and 482 population…
Comparison
Higher levels of adipose tissue alpha-linolenic… vs Lowest quintile of adipose tissue…
Design
Case-control
Authors
Discussion
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Member takes
Implication
Higher adipose ALA associated with lower MI risk; hypothesis-generating and should not yet change practice.
Structured PICO
Do higher levels of adipose tissue alpha-linolenic acid reduce the risk of nonfatal acute myocardial infarction?
P
Population
964 subjects in Costa Rica, comprising 482 case patients with a first nonfatal acute MI and 482 population control subjects matched by age, sex, and area of residence.
I
Intervention
Higher levels (top quintiles) of adipose tissue alpha-linolenic acid assessed by gas-liquid chromatography
C
Comparator
Lowest quintile of adipose tissue alpha-linolenic acid
O
Outcome
First nonfatal acute myocardial infarctionhard clinical
Higher adipose tissue levels of alpha-linolenic acid are associated with a substantially lower risk of nonfatal acute myocardial infarction, suggesting a protective cardiovascular effect.
Cite This Study
Baylín et al. (2003) studied this question.