Why the study?
It was unknown whether there is equitable distribution across sexes of treatment and outcomes for surgical or transcatheter aortic valve replacement in symptomatic severe aortic stenosis.
Does female sex affect the likelihood of undergoing aortic valve replacement and 1-year mortality in patients with symptomatic severe aortic stenosis?
Does female sex affect the likelihood of undergoing aortic valve replacement and 1-year mortality in patients with symptomatic severe aortic stenosis?
In patients with symptomatic severe aortic stenosis, females are less likely to undergo aortic valve replacement and experience higher 1-year mortality when treated, particularly driven by surgical AVR.
No takes yet. Share an insight, caveat, or question.
Females with severe AS show lower AVR rates and higher post-AVR mortality; leaves open whether disparities reflect bias, biology, or unmeasured factors.
Lowenstern et al. (2021) studied this question.