Key result
Transapical TAVI in patients with porcelain aorta was associated with a lower mean stroke rate compared to transfemoral TAVI (0.8% vs 9.0% in pooled literature review).
Why the study?
To evaluate early and mid-term outcomes of TA-TAVI versus TF-TAVI for aortic stenosis and porcelain aorta, hypothesizing TA-TAVI may have more favorable neurological outcomes.
Does TA-TAVI reduce stroke and mortality compared to TF-TAVI in patients with aortic stenosis and porcelain aorta?
Comparison
TA-TAVI vs TF-TAVI
Design
Single-center cohort study and systematic literature review
Follow-up
2-year
Authors
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May favor TA-TAVI over TF-TAVI in porcelain aorta to reduce stroke; leaves open need for randomized confirmation.
Systematic Review (n=19)
Does TA-TAVI reduce stroke and mortality compared to TF-TAVI in patients with aortic stenosis and porcelain aorta?
Absolute Event Rate: 0.8% vs 9%
In patients with aortic stenosis and porcelain aorta, TA-TAVI is associated with lower rates of stroke compared to TF-TAVI, with comparable early mortality.
Useini et al. (2019) conducted a systematic review in Aortic stenosis and porcelain aorta (n=19). Transapical transcatheter aortic valve implantation (TA-TAVI) vs. Transfemoral transcatheter aortic valve implantation (TF-TAVI) was evaluated on Mean stroke rate (pooled results). Transapical TAVI in patients with porcelain aorta was associated with a lower mean stroke rate compared to transfemoral TAVI (0.8% vs 9.0% in pooled literature review).
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