Population
36 hearts with congenital polyvalvular disease, often associated clinically with trisomy 18 or trisomy 13-15.
Design
Case_series
Authors
Loading...
Histology from one case highlights distinct valvular dysplasia; extends pathologic description but leaves generalizability open.
Congenital polyvalvular disease is characterized by specific dysplastic changes in all valves, distinct from hemodynamic changes, and is often associated with trisomy 18 or 13-15.
Bharati et al. (1973) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: