Key result
Radiofrequency ablation and multivalvular replacement were required to treat medically refractory multifocal ventricular arrhythmia and right heart failure in a female infant with congenital polyvalvular disease.
Case Report (n=1)
This case highlights the complex management of congenital polyvalvular disease requiring both electrophysiological and structural interventions in infancy.
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Hypothesis-generating for combined ablation and valve surgery in refractory infant polyvalvular disease; prospective data needed before clinical adoption.
We report the clinical course of a female child with a normal karyotype and chromosomal microarray who presented as an infant with clinical findings consistent with congenital polyvalvular disease (CPVD). This clinical entity describes patients with multiple congenitally dysplastic valves, often showing nodular or cystic malformation in at least two cardiac valves. This patient then developed medically refractory multifocal ventricular arrhythmia and required radiofrequency ablation at seven months of age. She had good tachycardia control but became symptomatic with right heart failure related to progressive tricuspid, pulmonary, and mitral valve dysfunction necessitating multivalvular replacement at 21 months of age.
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Goot et al. (2014) conducted a case report in Congenital polyvalvular disease (n=1). Radiofrequency ablation and multivalvular replacement was evaluated. Radiofrequency ablation and multivalvular replacement were required to treat medically refractory multifocal ventricular arrhythmia and right heart failure in a female infant with congenital polyvalvular disease.
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