Why the study?
Does U-63557A reduce thrombus mass in a canine model of coronary artery thrombosis?
Does U-63557A reduce thrombus mass in a canine model of coronary artery thrombosis?
Inhibition of TXA2 synthesis alone is insufficient to prevent occlusive coronary artery thrombosis in a canine model, suggesting the involvement of other mediators.
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TXA2 inhibition alone may not prevent coronary thrombosis in dogs; leaves open contributions of other mediators for future study.
Hook et al. (1985) studied this question.
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