Key result
Recurrent squamous cell carcinoma of the hypopharynx in a 62-year-old male resulted in a rare pericardial metastasis, which was detected via computed tomography and transthoracic echocardiogram.
Why the study?
Cardiac metastatic disease is rare and usually diagnosed incidentally postmortem, with pericardial metastasis from recurrent laryngopharyngeal tumors being very rarely reported.
Case Report (n=1)
No
This case highlights the rare occurrence of pericardial metastasis from recurrent squamous cell carcinoma of the hypopharynx, emphasizing the utility of echocardiography and CT in diagnosis.
May prompt cardiac imaging in recurrent hypopharyngeal cancer; leaves open questions on prevalence and outcomes.
Cardiac metastatic disease is a rare finding and is usually diagnosed incidentally postmortem; it has been commonly reported in patients with cancers of lung, esophagus, breast, and melanoma. We present a case of a 62-year-old male with a history of squamous cell carcinoma of the pyriform sinus who presented with shortness of breath for one day. He underwent tumor resection followed by chemotherapy and radiotherapy seven months before this presentation. Computed tomography (CT) of the chest revealed pericardial nodular soft tissue that was consistent with the diagnosis of metastatic carcinomatosis. Further imaging with a transthoracic echocardiogram (TTE) showed a likely metastatic pericardial mass. The patient had presented with shortness of breath three months prior to this admission and TTE had demonstrated pericardial effusion. However, pericardial fluid cytology was negative for malignancy, and the repeat TTE had revealed resolution of the pericardial effusion. On the current admission, CT of the neck demonstrated local recurrence of the tumor in the resection bed with scattered regional lymph nodes enlargement. Thus, we report a case of a recurrent laryngopharyngeal tumor with very rarely reported pericardial metastasis.
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Antala et al. (2022) conducted a case report in Squamous cell carcinoma of the pyriform sinus with pericardial metastasis (n=1). Recurrent squamous cell carcinoma of the hypopharynx in a 62-year-old male resulted in a rare pericardial metastasis, which was detected via computed tomography and transthoracic echocardiogram.
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