What does this research mean for the field?

Secondary malignant tumors of the pericardium occur in approximately 1.4% of patients, most commonly arising from lung, breast, and hematologic malignancies, and frequently cause fatal cardiac impairment via pericardial effusion that is often clinically underdiagnosed. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

August 1, 1962Circulation

Secondary Malignant Tumors of the Pericardium

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Structured PICO

Population

13,314 necropsies following death from neoplastic and nonneoplastic diseases performed at the Mayo Clinic from 1942 through 1958, including 189 cases of secondary malignant lesions of the pericardium (55 with impaired cardiac function).

Outcome

Incidence, mechanisms of cardiac impairment, and clinical presentation of secondary malignant lesions of the pericardium

Secondary malignant tumors of the pericardium occur in about 1.4% of necropsies, often causing cardiac impairment through pericardial effusion and tamponade, though frequently undiagnosed antemortem.

Discussion

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Implication

Supports consideration of malignancy in unexplained pericardial effusion; leaves open prospective validation of antemortem detection strategies.

Cite This Study

Thurber et al. (1962) studied this question.

synapsesocial.com/papers/6a1c049db33628da419d1e2a https://doi.org/10.1161/01.cir.26.2.228

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Implication

Supports consideration of malignancy in unexplained pericardial effusion; leaves open prospective validation of antemortem detection strategies.

Secondary Malignant Tumors of the Pericardium

Structured PICO

Discussion

Implication

Cite This Study

Secondary Malignant Tumors of the Pericardium

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider