What question did this study set out to answer?

To document and evaluate the clinical utility of examining pericardial fluid for the ante-mortem diagnosis of metastatic tumors involving the heart.

Carcinoma Diagnosed by Examination of Pericardial Fluid

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To document and evaluate the clinical utility of examining pericardial fluid for the ante-mortem diagnosis of metastatic tumors involving the heart.
Reviewed documented clinical literature regarding ante-mortem diagnoses of secondary cardiac and pericardial neoplasms.
Analyzed pericardial effusion samples via fluid examination to detect metastatic malignant cells during life.
Metastatic tumors of the heart and pericardium occur in 6% to 10% of all malignant neoplasms.
Ante-mortem identification remains rare, with prior American literature noting only 5 to 10 accurately diagnosed cases before death.

Population

Patients with metastatic tumors of the heart and pericardium

Intervention

Examination of pericardial fluid

Outcome

Ante-mortem diagnosis of carcinoma

Ante-mortem diagnosis of metastatic carcinoma to the heart and pericardium can be achieved through examination of pericardial fluid.

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May aid ante-mortem detection of cardiac metastases via pericardial fluid cytology; leaves open diagnostic performance and clinical utility.

Leichtling et al. (1952) studied this question.

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May aid ante-mortem detection of cardiac metastases via pericardial fluid cytology; leaves open diagnostic performance and clinical utility.