Key result
Administration of atosiban for premature labor in a 46-year-old pregnant woman with twins resulted in the development of life-threatening non-cardiogenic pulmonary edema requiring intensive care.
Why the study?
The authors sought to highlight the occurrence of non-cardiogenic pulmonary edema related to atosiban administration and emphasize distinguishing cardiogenic from non-cardiogenic pulmonary edema.
Case Report (n=1)
No
Atosiban administration for tocolysis may be associated with the rare but life-threatening complication of non-cardiogenic pulmonary edema.
Alerts clinicians to possible non-cardiogenic pulmonary edema with atosiban tocolysis; single case leaves open causality and true incidence.
We report the case of a pregnant woman, treated with atosiban for premature labor, who developed non-cardiogenic pulmonary edema. She corresponded initially to oxygen supplementation and furosemide administration to induce diuresis but the onset of preterm contractions combined with aggravation of respiratory failure led the patient to a cesarean section, and subsequently to the intensive care unit where she remained intubated for 24 hours. In this case report, we emphasize the importance of distinguishing between two types of pulmonary edema: cardiogenic and non-cardiogenic. The instant separation between these two categories, most of the time with transthoracic echocardiography while the patient is on early support of ventilation, increases the optimum outcome for the patient.
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Dalkalitsis et al. (2023) conducted a case report in Threatened preterm labor and non-cardiogenic pulmonary edema (n=1). Atosiban was evaluated on Development of non-cardiogenic pulmonary edema. Administration of atosiban for premature labor in a 46-year-old pregnant woman with twins resulted in the development of life-threatening non-cardiogenic pulmonary edema requiring intensive care.
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