Why the study?
Does smoking status affect 1-year mortality in patients with acute STEMI managed by primary PCI?
Population
1,796 patients with acute ST-segment elevation myocardial infarction managed by primary percutaneous…
Comparison
Current smoking or ex-smoking vs Never smoking
Design
Cohort
Follow-up
1 year
Key result
Current smoking was not associated with 1-year mortality compared with never smoking in patients with acute STEMI treated with primary PCI (HR 1.47; 95% CI 0.90-2.39; p=0.23).
Authors
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Smoking status should not alter prognosis or risk stratification after primary PCI for STEMI; this cohort study leaves open whether a smoker's paradox exists after adjustment.
Cohort (n=1,796)
No
Does smoking status affect 1-year mortality in patients with acute STEMI managed by primary PCI?
Effect estimate: HR 1.47 (95% CI 0.90 to 2.39)
p-value: p=0.23
In patients with STEMI undergoing primary PCI, smoking status was not significantly associated with 1-year mortality after adjusting for age and other risk factors, challenging the existence of a 'smoker's paradox'.
Steele et al. (2017) conducted a cohort in Acute ST-segment elevation myocardial infarction (STEMI) (n=1,796). Current smoking vs. Never smoking was evaluated on 1-year mortality (HR 1.47, 95% CI 0.90 to 2.39, p=0.23). Current smoking was not associated with 1-year mortality compared with never smoking in patients with acute STEMI treated with primary PCI (HR 1.47; 95% CI 0.90-2.39; p=0.23).