Impact of smoking status on outcome in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention
Why the study?
Does current smoking status reduce 1-year mortality in patients with STEMI treated with primary PCI?
Population
1,086 patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary…
Comparison
Current smoking status at STEMI presentation vs Non-smoking status at STEMI presentation
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
No mortality benefit from smoking after age/gender adjustment in STEMI; confirms confounding explains the paradox and leaves residual factors open.
Structured PICO
Does current smoking status reduce 1-year mortality in patients with STEMI treated with primary PCI?
P
Population
1,086 patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) enrolled in the EUROTRANSFER Registry.
I
Intervention
Current smoking status at STEMI presentation
C
Comparator
Non-smoking status at STEMI presentation
O
Outcome
Mortality at 1 yearhard clinical
The apparent 'smoker's paradox' of lower mortality in STEMI patients undergoing primary PCI is explained by differences in baseline characteristics, particularly younger age and male sex, rather than a protective effect of smoking.
Cite This Study
Rakowski et al. (2012) studied this question.