Key result
Higher BMI linked to ~10% increased odds of non-calcified coronary plaque in zero-CAC patients.
Why the study?
Data linking pericardial fat volume and classical coronary risk factors with non-calcified plaque presence among patients with CAC = 0 are scarce.
Do increased pericardial fat volume and high BMI predict the presence of non-calcified coronary plaque in patients with stable chest pain and a CAC score of 0?
Observational (n=417)
No
Do increased pericardial fat volume and high BMI predict the presence of non-calcified coronary plaque in patients with stable chest pain and a CAC score of 0?
In patients with stable chest pain and a CAC score of 0, high BMI is an independent predictor of the presence of non-calcified coronary plaque.
INTRODUCTION: There is scarce data linking pericardial fat volume (PFV) and classical coronary risk factors with non-calcified plaque presence among patients with CAC = 0 in the literature. MATERIAL AND METHOD: A total of 811 patients with chest pain suggestive of angina underwent CT coronary angiography for the assessment of coronary artery disease were collected. Of these, 417 with CAC = 0 were included in the analysis. RESULT: , P < 0.01) compared to patients without plaque. In multivariate regression analysis, high BMI[OR(CI) = 1.1(1-1.3), P = 0.02] was an independent predictor of non-calcified coronary plaque presence among patients with CAC = 0 after adjustment to variables with P < 0.05 in the univariate analysis. CONCLUSION: In patients with a CAC score of 0, advanced age, diabetes mellitus, increased PFV, and high BMI were all associated with the presence of non-calcified plaque. After multivariate adjustment, increased BMI remained a significant independent predictor for non-calcified plaque presence.
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Al‐Mosawi et al. (2023) conducted an observational in Suspected coronary artery disease with CAC = 0 (n=417). Body mass index (BMI) vs. Lower BMI was evaluated on Presence of non-calcified coronary plaque (OR 1.1, 95% CI 1-1.3, p=0.02). Among patients with suspected coronary artery disease and a calcium score of 0, higher body mass index was an independent predictor of non-calcified coronary plaque presence (OR 1.1).
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