The Association of Pericardial Fat With Calcified Coronary Plaque
Why the study?
Is pericardial fat volume associated with calcified coronary plaque in adults without symptomatic coronary heart disease?
Population
159 whites and blacks without symptomatic coronary heart disease, aged 55-74 years, from Forsyth County, NC.
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Pericardial fat may mark higher plaque risk in asymptomatic adults; leaves open causality and incremental value for risk stratification.
Structured PICO
Is pericardial fat volume associated with calcified coronary plaque in adults without symptomatic coronary heart disease?
P
Population
159 whites and blacks without symptomatic coronary heart disease, aged 55-74 years, from Forsyth County, NC (subset of the Multi-Ethnic Study of Atherosclerosis [MESA]).
I
Intervention
Pericardial fat volume measured by computed tomography (CT) scan
O
Outcome
Presence of calcified coronary plaque assessed by CT scansurrogate
Pericardial fat volume is independently associated with the presence of calcified coronary plaque, suggesting a local pathogenic effect of visceral adiposity on coronary atherosclerosis.
Cite This Study
Ding et al. (2008) studied this question.