Key result
64-slice computed tomography yielded slightly higher left atrial (56 vs 54 mL, P=0.003) and ventricular (66 vs 57 mL, P=0.0001) volumes compared to water displacement, with low variability.
Why the study?
Does 64-slice CT accurately measure left atrial and ventricular volumes compared to water displacement in cardiac cadaveric casts?
Population
Human cardiac cadaveric silicone casts (left atrial n=14, left ventricular n=15)
Comparison
64-slice computed tomography imaging for volume… vs Water displacement (WD) as the gold standard
Design
Preclinical
Authors
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Should not yet change clinical volumetry; extends ex vivo validation of 64-slice CT.
Does 64-slice CT accurately measure left atrial and ventricular volumes compared to water displacement in cardiac cadaveric casts?
Absolute Event Rate: 56% vs 54%
p-value: p=0.003
64-slice CT is highly reproducible and accurate for assessing left atrial and ventricular volumes, though it slightly overestimates volumes compared to water displacement.
Järvinen et al. (2018) studied Human Cardiac Cadaveric Casts (n=29). 64-slice computed tomography (CT) vs. Water displacement (WD) was evaluated on Left atrial volume (p=0.003). 64-slice computed tomography yielded slightly higher left atrial (56 vs 54 mL, P=0.003) and ventricular (66 vs 57 mL, P=0.0001) volumes compared to water displacement, with low variability.
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