What question did this study set out to answer?

To evaluate the feasibility and accuracy of computed tomography for measuring left ventricular volume compared to conventional biplane angiocardiography.

May 1, 1978Radiology

Measurement of Left Ventricular Cast Volume by Computed Tomography

Q: What is the clinical evidence from this study?

Study design: Other. Population: Normal human left ventricles (n=24). Intervention: Computed tomography vs. Displacement method and conventional angiocardiographic biplane volume method. Primary outcome: Left ventricular volume measurement accuracy.

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Key result

Computed tomography for measuring left ventricular cast volume was independent of chamber orientation and significantly more accurate than conventional angiocardiographic biplane methods.

Why the study?

Does computed tomography improve the accuracy of left ventricular volume measurement compared to biplane methods in human left ventricle casts?

Population

Silastic casts of 24 normal human left ventricles

Comparison

Computed tomography for volume measurement vs Displacement method and conventional…

Design

Preclinical

Authors

MLMartin J. LiptonAmerican College of Cardiology THThomas HayashiCalifornia Department of Public Health DBDouglas P. BoydLangley Research Center

Discussion

Member takes

Implication

May support CT for LV volumetry research; leaves open clinical translation and human validation.

Key Points

To evaluate the feasibility and accuracy of computed tomography for measuring left ventricular volume compared to conventional biplane angiocardiography.
Evaluated Silastic casts prepared from normal human left ventricles (N=24).
Compared volume measurements across three techniques: a degassed fluid displacement standard using Archimedes' principle, conventional biplane angiocardiography, and computed tomography.
Biplane angiocardiographic measurements showed substantial variation around the regression line resulting from irregular chamber geometry and variations in orientation.
Computed tomographic measurements were independent of chamber orientation and demonstrated significantly greater accuracy than angiocardiography.

Structured PICO

Does computed tomography improve the accuracy of left ventricular volume measurement compared to biplane methods in human left ventricle casts?

Population

Silastic casts of 24 normal human left ventricles

Intervention

Computed tomography for volume measurement

Comparator

Displacement method (Archimedes' principle) and conventional angiocardiographic biplane volume method

Outcome

Accuracy of volume measurementsurrogate

Computed tomography provides more accurate left ventricular volume measurements than conventional biplane angiocardiography, independent of chamber orientation.

Cite This Study

Lipton et al. (1978) studied Normal human left ventricles (n=24). Computed tomography vs. Displacement method and conventional angiocardiographic biplane volume method was evaluated on Left ventricular volume measurement accuracy. Computed tomography for measuring left ventricular cast volume was independent of chamber orientation and significantly more accurate than conventional angiocardiographic biplane methods.

synapsesocial.com/papers/6a0ede2e37aeb0126447b2fd https://doi.org/10.1148/127.2.419

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Measurement of Left Ventricular Cast Volume by Computed Tomography

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Measurement of Left Ventricular Cast Volume by Computed Tomography

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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