Key result
A higher SYNTAX score was significantly associated with the presence of calcified carotid plaques in both the left (OR 1.04) and right (OR 1.04) internal carotid arteries.
Why the study?
While carotid artery ultrasound findings have been linked to CAD, the relationship between carotid plaque types and the complexity of coronary lesions has not been assessed.
Does the SYNTAX score predict carotid plaque morphology in patients undergoing coronary bypass surgery?
Observational (n=407)
Does the SYNTAX score predict carotid plaque morphology in patients undergoing coronary bypass surgery?
In patients undergoing CABG, a higher SYNTAX score is independently associated with the presence of calcified carotid plaques.
Should not alter carotid screening in CABG; leaves open whether SYNTAX predicts plaque morphology prospectively.
Objectives: Although there are many studies assessing the relationship between carotid artery ultrasound findings and coronary artery disease, the relationship between carotid plaque types and the complexity of coronary lesions is not assessed. We aimed to examine the relationship between the SYNTAX score and carotid plaque morphology. Patients and Methods: We retrospectively screened patients who underwent carotid Ultrasound before the coronary artery bypass graft operation between 2015 and 2020. Syntax score was calculated by two independent interventional cardiologists with online SYNTAX score calculator (www.syntaxscore.com). The lesions of carotid arteries by ultrasound were classified as fibrous, calcific and mixed plaques. Results: A total of 407 patients were enrolled. Median age was 65 (58-71) years and 81.6% of patients were male. We used multinomial logistic regression to test the association between plaque types and syntax score. The syntax score was associated with calcified plaque both in right (odds ratio 1.04, 95% CI 1.01-1.07, p=0.006) and left internal carotid artery (odds ratio 1.04, 95% CI 1.02-1.06, p=0.004). However, the syntax score was not associated with fibrous (odds ratio 0.97, 95% CI 0.94-1.01, p=0.155 for right and odds ratio 0.99, 95% CI 0.96-1.02, p=0.759 for left carotid artery) and mixed plaque types (odds ratio 1.02, 95% CI 0.98-1.06, p=0.168 for right and odds ratio 1.00, 95% CI 0.96-1.04, p=0.791 for left carotid artery). Conclusion: Syntax score may provide an idea for carotid plaque morphology prediction. Especially higher SYNTAX score may be a predictor of calcific carotid plaque.
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Aksoy et al. (2021) conducted an observational in Coronary artery disease (n=407). SYNTAX score vs. No plaque was evaluated on Association of SYNTAX score with calcified plaque in the left internal carotid artery (OR 1.04, 95% CI 1.02-1.06, p=0.004). A higher SYNTAX score was significantly associated with the presence of calcified carotid plaques in both the left (OR 1.04) and right (OR 1.04) internal carotid arteries.
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